永齡學者

腫瘤醫學研究所 歐大諒 專案副教授

獲獎年度:2020-2021

研究專長:癌症分子標靶治療、癌症轉移之機轉、腫瘤生物學醫學分子檢驗學

近5年論文 Recent Publications

1.

Lai HH, Li CW, Hong CC, Sun HY, Chiu CF, Ou DL, Chen PS. TARBP2-mediated destabilization of Nanog overcomes sorafenib resistance in hepatocellular carcinoma Mol Oncol. 2019 Jan 18. doi: 10.1002/1878-0261.12449. (Corresponding author)

2.

Lin YY, Tan CT, Chen CW, Ou DL, Cheng AL, Hsu C. Immunomodulatory Effects of Current Targeted Therapies on Hepatocellular Carcinoma: Implication for the Future of Immunotherapy. Seminar in Liver Disease 2018 Nov; 38: 379-88

3.

Shao YY, Chen BB, Ou DL, Lin ZZ, Hsu CH, Wang MJ, Cheng AL, Hsu C. Lenalidomide as second-line therapy for advanced hepatocellular carcinoma: exploration of biomarkers for treatment efficacy. Alimentary Pharmacology & Therapeutics 2017 Oct; 46: 722-30.

4.

Lin YZ, Ou DL, Chang HY, Lin WY, Hsu C, Chang PL. Simultaneous visualization of the subfemtomolar expression of microRNA and microRNA target gene using HILO microscopy. Chemical Science. 2017 Sep 1;8(9):6670-6678.

5.

H Lu JW, Wang AN, Liao HA, Chen CY, Hou HA, Hu CY, Tien HF, Ou DL, Lin LI: Cabozantinib is selectively cytotoxic in acute myeloid leukemia cells with FLT3-internal tandem duplication (FLT3-ITD) Article reference: Cancer Lett. 2016 Jul 1;376(2):218-25. (Corresponding author)

6.

Hsu C, Lin LI, Cheng YC, Feng ZR, Shao YY, Cheng AL, Ou DL. Cyclin E1 inhibition can overcome sorafenib resistance in hepatocellular carcinoma cells through Mcl-1 suppression. Clinical Cancer Research 2016 May; 22: 2555-64 (Corresponding author)

7.

Lu JW, Ho YJ, Yang YJ, Liao HA, Ciou SC, Lin LI, Ou DL. Zebrafish as a disease model for studying human hepatocellular carcinoma. World Journal of Gastroenterology. 2015 Nov 14;21(42):12042-58. (Corresponding author)

8.

Lu JW, Lin YM, Lai YL, Chen CY, Hu CY, Tien HF, Ou DL, Lin LI. MK-2206 induces apoptosis of AML cells and enhances the cytotoxicity of cytarabine. Medical Oncology. 2015 Jul;32(7):650. (Corresponding author)

9.

Wu PC, Lu JW, Yang JY, Lin IH, Ou DL, Lin YH, Chou KH, Huang WF, Wang WP, Huang YL, Hsu C, Lin LI, Lin YM, Shen CK, Tzeng TY.  H3K9 Histone Methyltransferase, KMT1E/SETDB1, Cooperates with the SMAD2/3 Pathway to Suppress Lung Cancer Metastasis. Cancer Research. 2014 Dec 15;74(24):7333-43

10.

Ou DL, Chang CJ, Jeng YM, Lin YJ, Lin ZZ, Gandhi AK, Liao SC, Huang ZM, Hsu C, Cheng AL. Potential synergistic anti-tumor activity between lenalidomide and sorafenib in hepatocellular carcinoma. Journal of Gastroenterology and Hepatology. 2014 Dec;29(12):2021-31. (First author)